Various transmucosal fentanyl preparations are available with similar onset of action and alternative routes of delivery:
- buccal tablets
- intranasal spray
- sublingual tablets
- lozenges
- buccal films
The most appropriate route of administration will depend on the patient’s preference, their manual dexterity and other clinical circumstances. These medications all require careful individual dose titration according to the product literature and patient response.
Transmucosal fentanyl citrate preparations:
Oro-mucosal products:
Abstral®:
100, 200, 300, 400, 600 and 800 microgram sublingual tablets
Actiq® lozenges with applicator:
200, 400, 600, 800, 1200, 1600 micrograms buccal lozenges
Breakyl® film (buccal):
200, 400, 800 microgram films
Effentora® buccal/sub-lingual tablets:
100, 200, 400, 600 and 800 microgram tablets
Recivit® sub-lingual tablets:
133, 267, 400, 533, 800 microgram tablets
Nasal Sprays:
PecFent® nasal spray:
100 , 400 microgram metered sprays
Please see http://www.medicines.org.uk/emc/
Summary of Product characteristics (SPC) for details of administration for the individual preparations.